How do antiplatelet drugs work?

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Louie Kuvalis asked a question: How do antiplatelet drugs work?
Asked By: Louie Kuvalis
Date created: Tue, Jun 1, 2021 3:21 PM
Date updated: Thu, Jun 23, 2022 9:13 AM

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#backtothebasics: how do antiplatelet drugs work?

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Antiplatelets are a group of medicines that stop blood cells (called platelets) from sticking together and forming a blood clot. Whenever there is an injury in your body, platelets are sent to the site of the injury, where they clump together to form a blood clot. This stops the bleeding in your body.

  • ZONTIVITY, aspirin, and clopidogrel are all a type of medication called antiplatelet therapy. These medications work by preventing platelets from sticking together to form a blood clot. Aspirin and clopidogrel each prevent platelets from sticking together to form blood clots in different ways.

Video answer: Antiplatelet drugs

Antiplatelet drugs

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Antiplatelet drugs are a group of powerful medicines that prevent blood clots. When you are wounded, platelets arrive on the scene and group together to form a clot that stops the bleeding. This is...

Antiplatelets are medicines that stop cells in the blood (platelets) from sticking together and forming a clot. A blood clot can lead to a heart attack or stroke. Aspirin is the most common antiplatelet. At a low dose, aspirin reduces inflammation in the arteries.

An antiplatelet drug (antiaggregant), also known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation. They are effective in the arterial circulation where anticoagulants have little effect.

Antiplatelet drugs inhibit thrombus formation — it is believed that this is how they exert their cardiovascular protective effect. Four main types of antiplatelet drugs are available: Aspirin irreversibly inhibits cyclo-oxygenase and blocks the production of thromboxane. Clopidogrel, prasugrel and ticagrelor are thienopyridines.

Both antiplatelets and anticoagulants work to prevent clots in your blood vessels, but they work in different ways. Antiplatelets interfere with the binding of platelets, or the process that...

Aspirin is the most commonly used oral antiplatelet drug. It works by irreversibly inhibiting the cyclooxygenase enzyme (COX) activity in the prostaglandin synthesis pathway (PGH2). This prostaglandin is a precursor of thromboxane A2 (TXA2) and PGI2.

Antiplatelets are a group of medicines that stop blood cells (called platelets) from sticking together and forming a blood clot. Whenever there is an injury in your body, platelets are sent to the site of the injury, where they clump together to form a blood clot. This stops the bleeding in your body.

Currently available antiplatelet drugs interfere with one or more steps in the process of platelet release and aggregation2and produce a measurable reduction in the risk of thrombosis that cannot be dissociated from an increased risk of bleeding.3

Most people who have had a cardiac event take an antiplatelet drug. Antiplatelets include: ASA, also called acetylsalicylic acid (Aspirin, Asaphen, Entrophen, Novasen) Clopidogrel (Plavix) Prasugrel (Effient) Ticagrelor (Brilinta) Be aware: Generic names are listed first. Canadian brand names are in brackets. This list doesn’t include every brand name. If your prescription isn’t listed, your pharmacist is the best source for more information. What does it do? Platelets are tiny cell ...

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Video answer: Antiplatelet drugs & thrombus inhibitors

Antiplatelet drugs & thrombus inhibitors