Carfilzomib drug class?
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Video answer: Proteasome inhibitor drugs
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Carfilzomib is in a class of medications called proteasome inhibitors. It works by stopping or slowing the growth of cancer cells in your body.
Carfilzomib drug class
- Carfilzomib is in a class of medications called proteasome inhibitors. It works by stopping or slowing the growth of cancer cells in your body. How should this medicine be used? Carfilzomib comes as a powder to be mixed with liquid to be injected intravenously (into a vein).
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Generic name: carfilzomib (kar FILZ oh mib) Brand name: Kyprolis. Dosage forms: intravenous powder for injection (10 mg; 30 mg; 60 mg) Drug class: Proteasome inhibitors. Medically reviewed by Drugs.com on Nov 6, 2020. Written by Cerner Multum. Uses. Warnings.
Carfilzomib is in a class of medications called proteasome inhibitors. It works by stopping or slowing the growth of cancer cells in your body. How should this medicine be used? Carfilzomib comes as a powder to be mixed with liquid to be injected intravenously (into a vein).
Active Substance: carfilzomib: INN/Common name: carfilzomib: Pharmacotherapeutic Classes: Antineoplastic agents: Status: This medicine is authorized for use in the European Union: Company: Amgen Europe B.V. Market Date: 2015-11-19
Drug Type: Carfilzomib is a targeted therapy. Carfilzomib is classified as a Proteasome Inhibitor. (For more detail, see "How this drug works" below). What Carfilzomib Is Used For: Treatment of multiple myeloma Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful. How Carfilzomib Is Given: As an intravenous/IV (into the vein) infusion.
4 Administration - Kyprolis can be administered in a 50 mL or 100 mL intravenous bag of 5% Dextrose Injection, USP.Infuse over 10 or 30 minutes depending on the Kyprolis dose regimen [see Dosage and Administration (2.2)].Administer as an intravenous infusion. Flush the intravenous administration line with normal saline or 5% Dextrose
Carfilzomib is in a class of medications called proteasome inhibitors. It works by stopping or slowing the growth of cancer cells in your body. Are there other uses for this medicine? This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Carfilzomib 56 mg/m 2 IV on Days 1, 2, 8, 9, 15, 16, PLUS; Daratumumab 16 mg/kg IV on Days 1, 8, 15, 22, PLUS; Dexamethasone 20 mg PO/IV on Days 1, 2, 8, 9, 15, 16; then 40 mg PO/IV on Day 22; Cycles 3-6. Carfilzomib 56 mg/m 2 IV on Days 1, 2, 8, 9, 15, 16, PLUS; Daratumumab 16 mg/kg IV on Days 1 and 15, PLUS
Carfilzomib is a safe and effective new treatment option for patients with relapsed MM refractory to bortezomib and thalidomide or lenalidomide. Randomized head-to-head trials with bortezomib will assist in formulary and treatment decisions in the context of PIs as a drug class.
Carfilzomib is a tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds to the N-terminal threonine-containing active sites of the 20S proteasome, the proteolytic core particle within the 26S proteasome. Carfilzomib exhibited antiproliferative and proapoptotic activity in solid and hematologic tumor cells in vitro.