Can you eat grapefruit when taking thyroid medicine?

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Does grapefruit interfere with thyroid Meds?

• But grapefruit poses a potential risk to people on thyroid hormone replacement therapy. This is because grapefruit interferes with an enzyme known as CYP3A4 which the intestines use to break down certain compounds so that they can be absorbed. Many thyroid drugs, including levothyroxine, rely on CYP3A4 for metabolization and absorption. 2 

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There are about 100 drugs that can have dangerous and even life-threatening effects if you eat grapefruit or drink grapefruit juice while taking them, but levothyroxine, a thyroid hormone drug used...

Grapefruit's Effect on Thyroid Medication Grapefruit is a popular and wholesome breakfast food. According to the U.S. Department of Agriculture, grapefruit is the second leading citrus fruit consumed per capita in the United States. Grapefruits are rich in vitamin A, ascorbic acid, folic acid, potassium, fiber and flavonoids.

But grapefruit poses a potential risk to people on thyroid hormone replacement therapy. This is because grapefruit interferes with an enzyme known as CYP3A4 which the intestines use to break down certain compounds so that they can be absorbed. Many thyroid drugs, including levothyroxine, rely on CYP3A4 for metabolization and absorption.  

"can anyone taking 75 mg of synthroid (thyroxine) eat grapefruit?" Answered by Dr. David Sneid: Yes: But thyroid is ideally taken in the morning an hour before eating... Ask doctors free

So, you can eat grapefruit or drink grapefruit juice, but not during the same time as you take your medications. There is no direct evidence for arimidex , (anastrozole) but it is metabolized thru the liver, so best not to mix the 2.

The authors of a July 2013 report in Thyroid listed several foods and beverages you should stay away from including grapefruit, grapefruit juice, soy protein and coffee. These products decrease the absorption and thus the effectiveness of levothyroxine. Fiber supplements may also negatively affect absorption of the thyroid medication.

Clopidogrel depends on CYPs — the proteins that grapefruit limits — to work. Thus, it becomes less active when mixed with grapefruit. A study of 7 patients taking clopidogrel with 200 mL of either...

Goitrogenic foods: broccoli, cabbage, brussels sprouts, cauliflower, kale, spinach, turnips, soybeans, peanuts, linseed, pine nuts, millet, cassava, and mustard greens. Please note that the vegetables can be eaten in moderation but should always be cooked. Alcoholic beverages and tobacco. Sugar and flour.